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KMID : 0376419820060020055
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Chonbuk University Medical Journal
1982 Volume.6 No. 2 p.55 ~ p.60
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Influences of the Autonomic Nervous System on the RES activity in splenectomized rats.
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Abstract
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The present experiment was designed to investigate the influences of autonomic nervous system on the phagocytic function of reticuloendotheliaL (RE) system in splenectomized and nonsplenectomized rats.
The phagocytic activity was assessed by means of carbon clearance method after buscopan, neostigmine, and propranolol were administered into rats.
The following results were obtained
1. The phagocytic activity of RE system in the buscopan treated group was decreased significa1 ntly, but increased in neostigmine and propranolol treated groups compared with normal and control groups. And the phagocytic activity showed the most significant modulation at five hours after injection.
2. In splenectomized group, the phagocytic activity was not modulated after administration of buscopan, neostigmine and propranolol.
3. From these results, it is concluded that the influence of autonomic nervous system on the phagocytic function of reticuloendothelial system was manifested by intervention of spleen.
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KEYWORD
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